Methaqualone is a sedative and hypnotic medication. It was sold under the brand names Quaalude and Sopor among others, which contained 300 mg of methaqualone, and sold as a combination drug under the brand name Mandrax, which contained 250 mg methaqualone and 25 mg diphenhydramine within the same tablet, mostly in Europe. Commercial production of methaqualone was halted in the mid-1980s due to widespread abuse and addictiveness. [ … ] 

Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as “ludes” or “disco biscuits” due to its widespread use during the popularity of disco in the 1970s, or “sopers” (also “soaps”) in the United States and “mandrakes” and “mandies” in the United Kingdom, Australia and New Zealand. [ … ]

“Mandrax.” Wikipedia, Wikimedia Foundation, 14 May 2022, en.wikipedia.org/wiki/Methaqualone.

Resources:

• Mandrax on Wikipedia
• Mandrax on Drugs.com
• To see what happens to the brain on drugs play to the game “Mouse Party” | Genetic Science Learning Center. “Mouse Party.” Learn.Genetics. August 30, 2013. Accessed December 25, 2021. https://learn.genetics.utah.edu/content/addiction/mouse/.